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Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Hybrid role (3+ days based at our Norwich office) Artlist is a leading creative technology company on a mission to empower creators and brands to bring their vision to life with video. Offering cutting-edge AI tools and models for image, video, and voiceover creation, alongside high-quality creative assets and powerful editing tools, Artlist enables creators to stay on trend, and achieve their creative goals. Trusted by over 30 million creators worldwide and top brands including Google, Amazon, Microsoft, and Versace, Artlist provides a seamless, subscription-based platform with a global license, giving creators everything they need to produce professional video content efficiently. For more information, visit artlist.io. Artlist is looking for an exceptional Senior Full-Stack Developer to join our new Platform Infrastructure team.
Hybrid role (3+ days based at our Norwich office) Artlist is a leading creative technology company on a mission to empower creators and brands to bring their vision to life with video. Offering cutting-edge AI tools and models for image, video, and voiceover creation, alongside high-quality creative assets and powerful editing tools, Artlist enables creators to stay on trend, and achieve their creative goals. Trusted by over 30 million creators worldwide and top brands including Google, Amazon, Microsoft, and Versace, Artlist provides a seamless, subscription-based platform with a global license, giving creators everything they need to produce professional video content efficiently. For more information, visit artlist.io. Artlist is looking for an exceptional Senior Full-Stack Developer to join our new Platform Infrastructure team.
RealVNC is the remote access platform for engineers looking for the most reliable and the most secure solution built by the creators of VNC technology. Over the last 25 years, as the inventors of VNC, we've enabled a global workforce to work wherever works and created the remote access market. Our software is used by hundreds of millions of users worldwide including IT professionals from global companies, such as Intel, IBM, NASA, Shell, DreamWorks and Philips. Our lead product, VNC Connect, allows users to connect securely to a remote device anywhere in the world, see its screen in real-time, and take control as though sitting in front of it. The product has been deployed across a myriad of use cases, from remote support through to deploying the software onto connected devices such as medical ventilators, set-top boxes, heavy industrial machinery and more.
RealVNC is the remote access platform for engineers looking for the most reliable and the most secure solution built by the creators of VNC technology. Over the last 25 years, as the inventors of VNC, we've enabled a global workforce to work wherever works and created the remote access market. Our software is used by hundreds of millions of users worldwide including IT professionals from global companies, such as Intel, IBM, NASA, Shell, DreamWorks and Philips. Our lead product, VNC Connect, allows users to connect securely to a remote device anywhere in the world, see its screen in real-time, and take control as though sitting in front of it. The product has been deployed across a myriad of use cases, from remote support through to deploying the software onto connected devices such as medical ventilators, set-top boxes, heavy industrial machinery and more.
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Senior Software Engineer plays a critical role in shaping, designing, and delivering the core systems that power our platform. You are responsible for defining and implementing high-quality software architectures that are reliable, scalable, and maintainable. Youll lead the design and development of services built around event-driven architectures, leveraging technologies such as Kafka, event sourcing, and stream processing to build systems that are both reacti
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Senior Software Engineer plays a critical role in shaping, designing, and delivering the core systems that power our platform. You are responsible for defining and implementing high-quality software architectures that are reliable, scalable, and maintainable. Youll lead the design and development of services built around event-driven architectures, leveraging technologies such as Kafka, event sourcing, and stream processing to build systems that are both reacti
We are looking for an experienced Senior NetSuite Software Engineer to join our Enterprise Systems team based in Cambridge, UK with remote or hybrid options considered. Reporting to the ERP Solutions Architect, you will take ownership of the full development lifecycle from solution design and technical documentation to development, testing, and deployment to deliver scalable, high-performing NetSuite solutions that empower our business operations. Youll collaborate closely with business stakeholders, solution architects, and cross-functional teams to translate complex requirements into elegant, maintainable NetSuite customizations and integrations. This position is ideal for someone who loves problem-solving, values their craft, and approaches challenges with a positive, can-do attitude. This role is offered on a hybrid basis, with a minimum of 3 days a week being bas
We are looking for an experienced Senior NetSuite Software Engineer to join our Enterprise Systems team based in Cambridge, UK with remote or hybrid options considered. Reporting to the ERP Solutions Architect, you will take ownership of the full development lifecycle from solution design and technical documentation to development, testing, and deployment to deliver scalable, high-performing NetSuite solutions that empower our business operations. Youll collaborate closely with business stakeholders, solution architects, and cross-functional teams to translate complex requirements into elegant, maintainable NetSuite customizations and integrations. This position is ideal for someone who loves problem-solving, values their craft, and approaches challenges with a positive, can-do attitude. This role is offered on a hybrid basis, with a minimum of 3 days a week being bas
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Engineering Delivery Manager (EDM) owns the delivery outcomes for one or more engineering teams ensuring that priorities, plans, and progress are clear, credible, and delivered as committed. This includes building and sustaining highperforming teams, aligning work with business priorities, and maintaining a consistent, trusted delivery narrative across the organisation. The EDM is accountable for engineering deliverables, working in close partnership with Tech
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Engineering Delivery Manager (EDM) owns the delivery outcomes for one or more engineering teams ensuring that priorities, plans, and progress are clear, credible, and delivered as committed. This includes building and sustaining highperforming teams, aligning work with business priorities, and maintaining a consistent, trusted delivery narrative across the organisation. The EDM is accountable for engineering deliverables, working in close partnership with Tech
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Proficiency in API design and integration.
Proficiency in API design and integration.
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
AI Engineer, Software Engineer, Machine Learning Engineer, LLM, GenAI, Agentic, LangChain, LangGraph, Langfuse, Python, Backend, API, MLflow, W&B, DVC, Evaluation, RAG, Retrieval, Semantic Search, Multimodal, Computer Vision, Speech-to-Text, Cloud, AWS, Azure, Model Deployment, UK Remote, Contractor, EdTech, Assessment Systems, Automated Scoring, Git, GitHub, UK Hours
AI Engineer, Software Engineer, Machine Learning Engineer, LLM, GenAI, Agentic, LangChain, LangGraph, Langfuse, Python, Backend, API, MLflow, W&B, DVC, Evaluation, RAG, Retrieval, Semantic Search, Multimodal, Computer Vision, Speech-to-Text, Cloud, AWS, Azure, Model Deployment, UK Remote, Contractor, EdTech, Assessment Systems, Automated Scoring, Git, GitHub, UK Hours
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Integrate automated API security testing workflows into the platform, ensuring reliability and accuracy of results.
Integrate automated API security testing workflows into the platform, ensuring reliability and accuracy of results.
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Familiarity with HTTP methods and API interaction design
Familiarity with HTTP methods and API interaction design
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RESTful API design and can build performant endpoints.
RESTful API design and can build performant endpoints.
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Deep understanding of API technologies (REST, GraphQL, XML-RPC)
Deep understanding of API technologies (REST, GraphQL, XML-RPC)
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• Strong backend engineering background delivering high-scale systems with AI components (Python/Java, RAG frameworks, vector databases, API engineering).
• Strong backend engineering background delivering high-scale systems with AI components (Python/Java, RAG frameworks, vector databases, API engineering).
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We are looking for a highly skilled Lead Business Analyst / Product Owner to lead the design, development, and delivery of API solutions that enable seamless integration across our digital ecosystem. This hybrid role combines strategic product ownership with hands-on business analysis to ensure our API platform meets business needs, enhances interoperability, and supports scalable growth. * Define and own the API product backlog, aligning with business objectives and technology strategy. * Act as the voice of the customer for API consumers, ensuring usability and developer experience. * Gather, analyze, and document functional and non-functional requirements for API development. * Collaborate with architects and engineering teams to design API specifications, JSON, XM
We are looking for a highly skilled Lead Business Analyst / Product Owner to lead the design, development, and delivery of API solutions that enable seamless integration across our digital ecosystem. This hybrid role combines strategic product ownership with hands-on business analysis to ensure our API platform meets business needs, enhances interoperability, and supports scalable growth. * Define and own the API product backlog, aligning with business objectives and technology strategy. * Act as the voice of the customer for API consumers, ensuring usability and developer experience. * Gather, analyze, and document functional and non-functional requirements for API development. * Collaborate with architects and engineering teams to design API specifications, JSON, XM
PREMIUM
Strong experience of working with and developing API endpoints.
Strong experience of working with and developing API endpoints.
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SPFx, TypeScript/JavaScript, Graph API, PnP PowerShell experience
SPFx, TypeScript/JavaScript, Graph API, PnP PowerShell experience
Your role as a GCP APIGEE specialist involves supporting teams with modern DevOps solutions, curating scalable GCP Cloud Products as IaaC, and building APIGEE/API solutions while modernising the APIGEE gateway. * Hands-on development and management of Google Apigee API Management Platform * Design, build, and deploy API proxies, policies, and configurations in Apigee * Implement CI/CD pipelines for API lifecycle management using tools like Jenkins, GitHub Actions, or Harness * Develop and maintain API security policies (OAuth, JWT, mTLS, rate limiting, threat protection) * Build automated workflows and scripts for API operations using Python * Manage API analytics, monitoring, and logging for performance and compliance * Enforce GCP Organization Polic
Your role as a GCP APIGEE specialist involves supporting teams with modern DevOps solutions, curating scalable GCP Cloud Products as IaaC, and building APIGEE/API solutions while modernising the APIGEE gateway. * Hands-on development and management of Google Apigee API Management Platform * Design, build, and deploy API proxies, policies, and configurations in Apigee * Implement CI/CD pipelines for API lifecycle management using tools like Jenkins, GitHub Actions, or Harness * Develop and maintain API security policies (OAuth, JWT, mTLS, rate limiting, threat protection) * Build automated workflows and scripts for API operations using Python * Manage API analytics, monitoring, and logging for performance and compliance * Enforce GCP Organization Polic
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Familiarity with integration tools and methods (e.g., API-based integrations, middleware solutions and automation platforms).
Familiarity with integration tools and methods (e.g., API-based integrations, middleware solutions and automation platforms).
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Contract: Automation Architect - Start Date: ASAP - Duration: 6 months - Location: Remote - UK - Rate: circa £550 - £590 per day outside of IR35 - This role is for a highly skilled and experienced Automation Architect responsible for the end-to-end delivery of on-premise private cloud infrastructure automation solutions. The ideal person will bridge the gap between architectural design, process analysis, and hands-on implementation, ensuring that infrastructure is provisioned and managed efficiently via Infrastructure as Code (IaC) principles utilizing a robust CI/CD pipeline orchestrated by Git runner technology. This automation will specifically target the deployment and management of environments hosting Containers (e.g., Kubernetes, OpenShift) and traditional Virtual Machines (VMs). Responsibilities - Strategy and Analysis
Contract: Automation Architect - Start Date: ASAP - Duration: 6 months - Location: Remote - UK - Rate: circa £550 - £590 per day outside of IR35 - This role is for a highly skilled and experienced Automation Architect responsible for the end-to-end delivery of on-premise private cloud infrastructure automation solutions. The ideal person will bridge the gap between architectural design, process analysis, and hands-on implementation, ensuring that infrastructure is provisioned and managed efficiently via Infrastructure as Code (IaC) principles utilizing a robust CI/CD pipeline orchestrated by Git runner technology. This automation will specifically target the deployment and management of environments hosting Containers (e.g., Kubernetes, OpenShift) and traditional Virtual Machines (VMs). Responsibilities - Strategy and Analysis
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Digital Product Information & Catalog Manager – Europe
Digital Product Information & Catalog Manager – Europe
Middleby Europe
Europe
£40,000 per annum Competitive Salary
Middlebys Digital Sales & Marketing team is expanding, and were looking for a Digital Product Information & Catalog Manager Europe to join us in a brand-new permanent role. If youre passionate about product data, system structure, and elevating the customer experience, this is your opportunity to make a big impact across a global organisation. About the Role - In this role, you will be the driver of product data excellence for Europeowning, managing, and optimising our Product Information Management (PIM) system. Youll ensure product data is accurate, consistent, enriched, and aligned across regions and channels. Working closely with cross-functional teams across Europe and the U.S., youll collaborate with the U.S.-based PIM Architect to evolve our data model for European needs, champion data governance standards, and lead the consistent publishing of product informat
Middlebys Digital Sales & Marketing team is expanding, and were looking for a Digital Product Information & Catalog Manager Europe to join us in a brand-new permanent role. If youre passionate about product data, system structure, and elevating the customer experience, this is your opportunity to make a big impact across a global organisation. About the Role - In this role, you will be the driver of product data excellence for Europeowning, managing, and optimising our Product Information Management (PIM) system. Youll ensure product data is accurate, consistent, enriched, and aligned across regions and channels. Working closely with cross-functional teams across Europe and the U.S., youll collaborate with the U.S.-based PIM Architect to evolve our data model for European needs, champion data governance standards, and lead the consistent publishing of product informat
Fast-growing FinTech and Tech For Good scale-up. * PHP, Laravel, Docker, CI/CD, AWS. * Remote UK, career development/training. A hugely successful, rapidly growing fin-tech company are looking for a Back-End/DevOps Engineer to join an established, small development team across their user-friendly platforms with new integrations and products. With a 4.8/5 Trustpilot score and a string of industry awards and recent investment, theyre ready to grow by another 70% next year. They need an experienced PHP/Laravel Developer with some DevOps experience in AWS or similar who has experience managing and configuring Docker environments for production. What experience youll need * Experience building and shipping production apps using PHP, Laravel APIs. * DevOps experience in AWS or similar. * Experience configuring and managing Docker environments for production, CI/CD and using
Fast-growing FinTech and Tech For Good scale-up. * PHP, Laravel, Docker, CI/CD, AWS. * Remote UK, career development/training. A hugely successful, rapidly growing fin-tech company are looking for a Back-End/DevOps Engineer to join an established, small development team across their user-friendly platforms with new integrations and products. With a 4.8/5 Trustpilot score and a string of industry awards and recent investment, theyre ready to grow by another 70% next year. They need an experienced PHP/Laravel Developer with some DevOps experience in AWS or similar who has experience managing and configuring Docker environments for production. What experience youll need * Experience building and shipping production apps using PHP, Laravel APIs. * DevOps experience in AWS or similar. * Experience configuring and managing Docker environments for production, CI/CD and using
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My client are seeking a JavaDeveloper with strong expertise in Apache Kafka, Node.js, and AWS cloud services. The role involves designing and implementing scalable, event-driven architectures, building microservices, and deploying solutions in a cloud-native environment. Essential Skills & Experience * Strong commercial experience with Java (core + modern frameworks) * Hands-on experience with Node.js * Proven background delivering solutions in AWS environments * Understanding of microservices, APIs and distributed systems * Experience working in Agile / DevOps environments * Familiarity with CI/CD pipelines and cloud-native tooling * Experience with Kafka Desirable * Previous experience working in public-sector or secure environments
My client are seeking a JavaDeveloper with strong expertise in Apache Kafka, Node.js, and AWS cloud services. The role involves designing and implementing scalable, event-driven architectures, building microservices, and deploying solutions in a cloud-native environment. Essential Skills & Experience * Strong commercial experience with Java (core + modern frameworks) * Hands-on experience with Node.js * Proven background delivering solutions in AWS environments * Understanding of microservices, APIs and distributed systems * Experience working in Agile / DevOps environments * Familiarity with CI/CD pipelines and cloud-native tooling * Experience with Kafka Desirable * Previous experience working in public-sector or secure environments