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Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
At MHR, our employees are central to our success and play a key role in helping customers achieve sustainable high performance. With a team of over 900 professionals, we work to make things flow smoothly, whether it's for large organisations or individual employees. As businesses face rapid changes in the world of work, our team is here to help them adapt and thrive.€ By focusing on the core needs of efficiency, productivity, growth, and impact, our employees use their expertise to deliver real solutions through our People and Finance platform. This system, which covers finance, HR, payroll, and learning, helps businesses run more smoothly and make better decisions in real time. With over 40 years of experience behind us, MHRs track record as a high-performance organisation is built on clear goals, a shared vision, and strong communication - all of which we pass on to
At MHR, our employees are central to our success and play a key role in helping customers achieve sustainable high performance. With a team of over 900 professionals, we work to make things flow smoothly, whether it's for large organisations or individual employees. As businesses face rapid changes in the world of work, our team is here to help them adapt and thrive.€ By focusing on the core needs of efficiency, productivity, growth, and impact, our employees use their expertise to deliver real solutions through our People and Finance platform. This system, which covers finance, HR, payroll, and learning, helps businesses run more smoothly and make better decisions in real time. With over 40 years of experience behind us, MHRs track record as a high-performance organisation is built on clear goals, a shared vision, and strong communication - all of which we pass on to
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Principal Software Engineer (.Net)
Principal Software Engineer (.Net)
MHR International UK Limited
Nottingham, Nottinghamshire
Competitive
Microsoft Azure (Functions, AKS, App Service, API Management, Service Bus, Event Grid, Storage, Cosmos DB, Azure SQL)
Microsoft Azure (Functions, AKS, App Service, API Management, Service Bus, Event Grid, Storage, Cosmos DB, Azure SQL)
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Senior Software Engineer - Amazon Connect
Senior Software Engineer - Amazon Connect
Capital One (Europe) plc
Nottingham, Nottinghamshire
Competitive
This mainly consists of Lambda, API Gateway, DynamoDB, S3 and our own front end portal that sits on top of Amazon Connect. In particular any knowledge of running in a serverless ecosystem with AWS Lambda, API Gateway and DynamoDB.
This mainly consists of Lambda, API Gateway, DynamoDB, S3 and our own front end portal that sits on top of Amazon Connect. In particular any knowledge of running in a serverless ecosystem with AWS Lambda, API Gateway and DynamoDB.
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Familiarity with HTTP methods and API interaction design
Familiarity with HTTP methods and API interaction design
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Secure API integration: rate limiting, authentication, and governance via Azure API Management.
Secure API integration: rate limiting, authentication, and governance via Azure API Management.
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RESTful API design and can build performant endpoints.
RESTful API design and can build performant endpoints.
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Strong commercial experience with Node.js (Back End services and API development). * Knowledge of RESTful API design and integration.
Strong commercial experience with Node.js (Back End services and API development). * Knowledge of RESTful API design and integration.
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Are you an experienced Full Stack .Net (C#) Developer, with solid experience in API development, keen to take ownership of end-to-end development, contribute to product innovation, and grow in a tech-led, agile team that genuinely values your input?
Are you an experienced Full Stack .Net (C#) Developer, with solid experience in API development, keen to take ownership of end-to-end development, contribute to product innovation, and grow in a tech-led, agile team that genuinely values your input?
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• Strong backend engineering background delivering high-scale systems with AI components (Python/Java, RAG frameworks, vector databases, API engineering).
• Strong backend engineering background delivering high-scale systems with AI components (Python/Java, RAG frameworks, vector databases, API engineering).
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We are looking for a highly skilled Lead Business Analyst / Product Owner to lead the design, development, and delivery of API solutions that enable seamless integration across our digital ecosystem. This hybrid role combines strategic product ownership with hands-on business analysis to ensure our API platform meets business needs, enhances interoperability, and supports scalable growth. * Define and own the API product backlog, aligning with business objectives and technology strategy. * Act as the voice of the customer for API consumers, ensuring usability and developer experience. * Gather, analyze, and document functional and non-functional requirements for API development. * Collaborate with architects and engineering teams to design API specifications, JSON, XM
We are looking for a highly skilled Lead Business Analyst / Product Owner to lead the design, development, and delivery of API solutions that enable seamless integration across our digital ecosystem. This hybrid role combines strategic product ownership with hands-on business analysis to ensure our API platform meets business needs, enhances interoperability, and supports scalable growth. * Define and own the API product backlog, aligning with business objectives and technology strategy. * Act as the voice of the customer for API consumers, ensuring usability and developer experience. * Gather, analyze, and document functional and non-functional requirements for API development. * Collaborate with architects and engineering teams to design API specifications, JSON, XM
PREMIUM
Strong experience of working with and developing API endpoints.
Strong experience of working with and developing API endpoints.
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Digital Product Information & Catalog Manager – Europe
Digital Product Information & Catalog Manager – Europe
Middleby Europe
Europe
£40,000 per annum Competitive Salary
Middlebys Digital Sales & Marketing team is expanding, and were looking for a Digital Product Information & Catalog Manager Europe to join us in a brand-new permanent role. If youre passionate about product data, system structure, and elevating the customer experience, this is your opportunity to make a big impact across a global organisation. About the Role - In this role, you will be the driver of product data excellence for Europeowning, managing, and optimising our Product Information Management (PIM) system. Youll ensure product data is accurate, consistent, enriched, and aligned across regions and channels. Working closely with cross-functional teams across Europe and the U.S., youll collaborate with the U.S.-based PIM Architect to evolve our data model for European needs, champion data governance standards, and lead the consistent publishing of product informat
Middlebys Digital Sales & Marketing team is expanding, and were looking for a Digital Product Information & Catalog Manager Europe to join us in a brand-new permanent role. If youre passionate about product data, system structure, and elevating the customer experience, this is your opportunity to make a big impact across a global organisation. About the Role - In this role, you will be the driver of product data excellence for Europeowning, managing, and optimising our Product Information Management (PIM) system. Youll ensure product data is accurate, consistent, enriched, and aligned across regions and channels. Working closely with cross-functional teams across Europe and the U.S., youll collaborate with the U.S.-based PIM Architect to evolve our data model for European needs, champion data governance standards, and lead the consistent publishing of product informat
Fast-growing FinTech and Tech For Good scale-up. * PHP, Laravel, Docker, CI/CD, AWS. * Remote UK, career development/training. A hugely successful, rapidly growing fin-tech company are looking for a Back-End/DevOps Engineer to join an established, small development team across their user-friendly platforms with new integrations and products. With a 4.8/5 Trustpilot score and a string of industry awards and recent investment, theyre ready to grow by another 70% next year. They need an experienced PHP/Laravel Developer with some DevOps experience in AWS or similar who has experience managing and configuring Docker environments for production. What experience youll need * Experience building and shipping production apps using PHP, Laravel APIs. * DevOps experience in AWS or similar. * Experience configuring and managing Docker environments for production, CI/CD and using
Fast-growing FinTech and Tech For Good scale-up. * PHP, Laravel, Docker, CI/CD, AWS. * Remote UK, career development/training. A hugely successful, rapidly growing fin-tech company are looking for a Back-End/DevOps Engineer to join an established, small development team across their user-friendly platforms with new integrations and products. With a 4.8/5 Trustpilot score and a string of industry awards and recent investment, theyre ready to grow by another 70% next year. They need an experienced PHP/Laravel Developer with some DevOps experience in AWS or similar who has experience managing and configuring Docker environments for production. What experience youll need * Experience building and shipping production apps using PHP, Laravel APIs. * DevOps experience in AWS or similar. * Experience configuring and managing Docker environments for production, CI/CD and using
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We are seeking a skilled Full Stack Developer to lead the development of a scalable, secure, and user-centric analytics platform. This is a12 Months fixed term role, you must be UK based, the role is fully remote. Full Stack Developer - Role Responsibilities * Develop and maintain the React-based UI and Golang microservices backend * Design intuitive user experiences and deliver feature-rich portal modules * Implement and optimise CI/CD pipelines for automated deployment and testing. * Integrate with external * Build and manage APIs for internal and customer-facing services. * Participate in architectural decisions and contribute to the platforms roadmap. Full Stack Developer -Essential Experience * Proven experience in full stack development * Strong proficiency in React, JavaScript, PHP Symfony, and Golang
We are seeking a skilled Full Stack Developer to lead the development of a scalable, secure, and user-centric analytics platform. This is a12 Months fixed term role, you must be UK based, the role is fully remote. Full Stack Developer - Role Responsibilities * Develop and maintain the React-based UI and Golang microservices backend * Design intuitive user experiences and deliver feature-rich portal modules * Implement and optimise CI/CD pipelines for automated deployment and testing. * Integrate with external * Build and manage APIs for internal and customer-facing services. * Participate in architectural decisions and contribute to the platforms roadmap. Full Stack Developer -Essential Experience * Proven experience in full stack development * Strong proficiency in React, JavaScript, PHP Symfony, and Golang
FEATURED
Role/Job Title:SCADA Test Analyst - Work Location:Warwick, UK (Onsite) The Role: SCADA Test Analyst * Reporting into the ET SCADA Test Manager, each Test QA Analyst will be aligned to an agile workstream (either SCADA or EMS) to conduct Test Quality Assurance activities to ensure that the testing activities and artefacts produced by that workstream are of the required standard and scope. * Working with the supplier Test Manager and Technical SMEs, the workstream Product Owner, SCRUM Master and SCADA SMEs, the QA lead will represent the NGET Test QA function at agile ceremonies such as Sprint Planning, Daily Stand Ups and Retrospectives ensuring that testing activities are correctly represented as User Stories and that the right NG stakeholders are engaged. * Monitor and report on test readiness, preparation of Test Environments and reporting progress to SCRUM Teams an
Role/Job Title:SCADA Test Analyst - Work Location:Warwick, UK (Onsite) The Role: SCADA Test Analyst * Reporting into the ET SCADA Test Manager, each Test QA Analyst will be aligned to an agile workstream (either SCADA or EMS) to conduct Test Quality Assurance activities to ensure that the testing activities and artefacts produced by that workstream are of the required standard and scope. * Working with the supplier Test Manager and Technical SMEs, the workstream Product Owner, SCRUM Master and SCADA SMEs, the QA lead will represent the NGET Test QA function at agile ceremonies such as Sprint Planning, Daily Stand Ups and Retrospectives ensuring that testing activities are correctly represented as User Stories and that the right NG stakeholders are engaged. * Monitor and report on test readiness, preparation of Test Environments and reporting progress to SCRUM Teams an
Role/Job Title:Salesforce Release Manager - Work Location:Milton Keynes, UK (onsite) The Role - Strong background in Salesforce release management within regulated environments (preferably financial services or banking). Hands-on experience with Salesforce deployments (including use of version control, metadata APIs, and deployment automation tools). Your Responsibilities (Up to 10) * Experience coordinating Salesforce environments as part of complex release schedules. * Proven ability to plan and execute sandbox refreshes and manage environment data strategies. * Strong understanding of environment types and their use cases, including scratch orgs, sandboxes, and production. * Demonstrable understanding of differences between scratch orgs, sandboxes, and production environments, supporting appropriate release and testing strategies.
Role/Job Title:Salesforce Release Manager - Work Location:Milton Keynes, UK (onsite) The Role - Strong background in Salesforce release management within regulated environments (preferably financial services or banking). Hands-on experience with Salesforce deployments (including use of version control, metadata APIs, and deployment automation tools). Your Responsibilities (Up to 10) * Experience coordinating Salesforce environments as part of complex release schedules. * Proven ability to plan and execute sandbox refreshes and manage environment data strategies. * Strong understanding of environment types and their use cases, including scratch orgs, sandboxes, and production. * Demonstrable understanding of differences between scratch orgs, sandboxes, and production environments, supporting appropriate release and testing strategies.
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Do you want your coding skills to make a real difference? Join a mission-driven tech-for-good organisation and help build websites and digital tools that positively impact communities. Were looking for a talented WordPress Developerto take ownership of digital platforms. Youll work on everything from themes and custom plugins to integrations and cloud-based solutions, ensuring the sites are fast, secure, and scalable. * Fully remote within the UK * Salary up to £50,000 * 33 days annual leave * Pension & healthcare * A role with genuine social impact * A supportive, mission-driven workplace * Professional development and clear career progression * Building and enhancing WordPress websites with clean, maintainable code * Collaborating with designers, content creators, and stakeholders to bring digital ideas to life
Do you want your coding skills to make a real difference? Join a mission-driven tech-for-good organisation and help build websites and digital tools that positively impact communities. Were looking for a talented WordPress Developerto take ownership of digital platforms. Youll work on everything from themes and custom plugins to integrations and cloud-based solutions, ensuring the sites are fast, secure, and scalable. * Fully remote within the UK * Salary up to £50,000 * 33 days annual leave * Pension & healthcare * A role with genuine social impact * A supportive, mission-driven workplace * Professional development and clear career progression * Building and enhancing WordPress websites with clean, maintainable code * Collaborating with designers, content creators, and stakeholders to bring digital ideas to life
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Espire Infolabs is hiring forJDA Dispatcher Developer for UK with 100% remote working - Job Title:JDA Dispatcher Developer - Job Type: Permanent - Job Location: 100% Remote - Job Description, Develop & maintain custom enhancements, interfaces, and extensions within the JDA Dispatcher WMS environment. Design & implement system configurations, rules changes and new functionalities to meet evolving business needs. Participating in the implementation of new JDA Dispatcher systems, including configuring the system based on business requirements and conducting user training. Working on integrating the JDA Dispatcher WMS with other systems like ERP, TMS, and material handling equipment (MHE). Analysing and troubleshooting technical problems related to the JDA Dispatcher WMS, including performance issues, integration problems, and user-related operational issues.
Espire Infolabs is hiring forJDA Dispatcher Developer for UK with 100% remote working - Job Title:JDA Dispatcher Developer - Job Type: Permanent - Job Location: 100% Remote - Job Description, Develop & maintain custom enhancements, interfaces, and extensions within the JDA Dispatcher WMS environment. Design & implement system configurations, rules changes and new functionalities to meet evolving business needs. Participating in the implementation of new JDA Dispatcher systems, including configuring the system based on business requirements and conducting user training. Working on integrating the JDA Dispatcher WMS with other systems like ERP, TMS, and material handling equipment (MHE). Analysing and troubleshooting technical problems related to the JDA Dispatcher WMS, including performance issues, integration problems, and user-related operational issues.
FEATURED
Role: ServiceNow Architect - Location: Remote in Europe - Type: Contract (Outside IR35) Summary - We're seeking a seasoned ServiceNow Architect to lead enterprise-scale solution design, platform governance, and integration strategy across core ServiceNow products (ITSM, ITOM, HRSD, CSM). The ideal candidate also brings hands-on Salesforce experience to architect and deliver robust integrations and cross-platform processes. You will drive architectural standards, scalability, security, and value realization while guiding delivery teams and stakeholders. Key Responsibilities * Architecture & Solution Design - o Own end-to-end architecture across ServiceNow modules (e.g., ITSM, ITOM/Discovery/Service Mapping, HRSD, CSM, SPM/App Engine). o Define data models and align with CSDM standards; establish CMDB strategy, health, and governance.
Role: ServiceNow Architect - Location: Remote in Europe - Type: Contract (Outside IR35) Summary - We're seeking a seasoned ServiceNow Architect to lead enterprise-scale solution design, platform governance, and integration strategy across core ServiceNow products (ITSM, ITOM, HRSD, CSM). The ideal candidate also brings hands-on Salesforce experience to architect and deliver robust integrations and cross-platform processes. You will drive architectural standards, scalability, security, and value realization while guiding delivery teams and stakeholders. Key Responsibilities * Architecture & Solution Design - o Own end-to-end architecture across ServiceNow modules (e.g., ITSM, ITOM/Discovery/Service Mapping, HRSD, CSM, SPM/App Engine). o Define data models and align with CSDM standards; establish CMDB strategy, health, and governance.
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Job Title: Full Stack Developer - Location: London, UK (Hybrid Work Mode) Job Type: Permanent - We are seeking a Full Stack Developer with strong experience in web application development, particularly focusing on the integration of Generative AI and Agentic Application models. You will play a key role in building and enhancing innovative solutions that leverage both advanced front-end and back-end technologies in a cloud environment. * Develop robust web applications integrating Generative AI and Agentic Application models. * Design and build scalable, responsive front-end interfaces. * Create and maintain efficient back-end systems and APIs. * Integrate AI frameworks into applications and support deployment in cloud environments. * Collaborate with DevOps teams to implement CI/CD pipelines and manage infrastructure.
Job Title: Full Stack Developer - Location: London, UK (Hybrid Work Mode) Job Type: Permanent - We are seeking a Full Stack Developer with strong experience in web application development, particularly focusing on the integration of Generative AI and Agentic Application models. You will play a key role in building and enhancing innovative solutions that leverage both advanced front-end and back-end technologies in a cloud environment. * Develop robust web applications integrating Generative AI and Agentic Application models. * Design and build scalable, responsive front-end interfaces. * Create and maintain efficient back-end systems and APIs. * Integrate AI frameworks into applications and support deployment in cloud environments. * Collaborate with DevOps teams to implement CI/CD pipelines and manage infrastructure.
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Looking for a Technical Business Analyst to support squads across a high-profile digital environment. You'll work closely with technical and business teams, shaping requirements and supporting delivery from discovery through to live service. The role requires someone confident engaging directly with technical and business stakeholders, translating business needs into technical requirements, and supporting squads through the full lifecycle. * Gather and refine requirements with stakeholders * Translate discovery outputs into clear epics and user stories * Work with architects and developers to validate technical feasibility * Understand RESTful APIs, data flows, and integration patterns * Contribute to agile ceremonies and support iterative delivery * Work across legacy and modern service environments * Proven experience as a Technical BA within digital or engineering
Looking for a Technical Business Analyst to support squads across a high-profile digital environment. You'll work closely with technical and business teams, shaping requirements and supporting delivery from discovery through to live service. The role requires someone confident engaging directly with technical and business stakeholders, translating business needs into technical requirements, and supporting squads through the full lifecycle. * Gather and refine requirements with stakeholders * Translate discovery outputs into clear epics and user stories * Work with architects and developers to validate technical feasibility * Understand RESTful APIs, data flows, and integration patterns * Contribute to agile ceremonies and support iterative delivery * Work across legacy and modern service environments * Proven experience as a Technical BA within digital or engineering
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Job Title: Product Security Architect (Contract) Location: UK-based / Remote - Contract: 3 months initially, Outside IR35 - Why Apply? This is an opportunity to play a key role in shaping Product Security for an international technology organisation. The role offers exposure to a federated environment across multiple business units, providing strategic influence and hands on technical impact. * Define, lead, and evolve a group-wide Product Security and Secure SSDLC strategy across all business units. * Assess current AppSec capabilities, identify gaps, and implement practical, scalable improvements. * Collaborate with Product Architects, engineering, and security teams to integrate security into GitHub, CI/CD pipelines, and development workflows. * Provide architecture guidance and implement secure coding practices, threat modelling, and security tooling.
Job Title: Product Security Architect (Contract) Location: UK-based / Remote - Contract: 3 months initially, Outside IR35 - Why Apply? This is an opportunity to play a key role in shaping Product Security for an international technology organisation. The role offers exposure to a federated environment across multiple business units, providing strategic influence and hands on technical impact. * Define, lead, and evolve a group-wide Product Security and Secure SSDLC strategy across all business units. * Assess current AppSec capabilities, identify gaps, and implement practical, scalable improvements. * Collaborate with Product Architects, engineering, and security teams to integrate security into GitHub, CI/CD pipelines, and development workflows. * Provide architecture guidance and implement secure coding practices, threat modelling, and security tooling.
Understanding of API testing tools and frameworks (e.g., RestAssured, Postman).
Understanding of API testing tools and frameworks (e.g., RestAssured, Postman).
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ServiceNow Architect – Full Time Onsite (Abu Dhabi) Relocation from UK
ServiceNow Architect – Full Time Onsite (Abu Dhabi) Relocation from UK
NST Recruitment Ltd
UK
From £100,000 to £110,000 per annum GBP equivalent to AED - tax free (
The ServiceNow Architect needs good REST API knowledge as well as licence management.
The ServiceNow Architect needs good REST API knowledge as well as licence management.
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