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Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Drug Conjugate (BDC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials.
RealVNC is the remote access platform for engineers looking for the most reliable and the most secure solution built by the creators of VNC technology. Over the last 25 years, as the inventors of VNC, we've enabled a global workforce to work wherever works and created the remote access market. Our software is used by hundreds of millions of users worldwide including IT professionals from global companies, such as Intel, IBM, NASA, Shell, DreamWorks and Philips. Our lead product, VNC Connect, allows users to connect securely to a remote device anywhere in the world, see its screen in real-time, and take control as though sitting in front of it. The product has been deployed across a myriad of use cases, from remote support through to deploying the software onto connected devices such as medical ventilators, set-top boxes, heavy industrial machinery and more.
RealVNC is the remote access platform for engineers looking for the most reliable and the most secure solution built by the creators of VNC technology. Over the last 25 years, as the inventors of VNC, we've enabled a global workforce to work wherever works and created the remote access market. Our software is used by hundreds of millions of users worldwide including IT professionals from global companies, such as Intel, IBM, NASA, Shell, DreamWorks and Philips. Our lead product, VNC Connect, allows users to connect securely to a remote device anywhere in the world, see its screen in real-time, and take control as though sitting in front of it. The product has been deployed across a myriad of use cases, from remote support through to deploying the software onto connected devices such as medical ventilators, set-top boxes, heavy industrial machinery and more.
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Senior Software Engineer plays a critical role in shaping, designing, and delivering the core systems that power our platform. You are responsible for defining and implementing high-quality software architectures that are reliable, scalable, and maintainable. Youll lead the design and development of services built around event-driven architectures, leveraging technologies such as Kafka, event sourcing, and stream processing to build systems that are both reacti
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Senior Software Engineer plays a critical role in shaping, designing, and delivering the core systems that power our platform. You are responsible for defining and implementing high-quality software architectures that are reliable, scalable, and maintainable. Youll lead the design and development of services built around event-driven architectures, leveraging technologies such as Kafka, event sourcing, and stream processing to build systems that are both reacti
We are looking for an experienced Senior NetSuite Software Engineer to join our Enterprise Systems team based in Cambridge, UK with remote or hybrid options considered. Reporting to the ERP Solutions Architect, you will take ownership of the full development lifecycle from solution design and technical documentation to development, testing, and deployment to deliver scalable, high-performing NetSuite solutions that empower our business operations. Youll collaborate closely with business stakeholders, solution architects, and cross-functional teams to translate complex requirements into elegant, maintainable NetSuite customizations and integrations. This position is ideal for someone who loves problem-solving, values their craft, and approaches challenges with a positive, can-do attitude. This role is offered on a hybrid basis, with a minimum of 3 days a week being bas
We are looking for an experienced Senior NetSuite Software Engineer to join our Enterprise Systems team based in Cambridge, UK with remote or hybrid options considered. Reporting to the ERP Solutions Architect, you will take ownership of the full development lifecycle from solution design and technical documentation to development, testing, and deployment to deliver scalable, high-performing NetSuite solutions that empower our business operations. Youll collaborate closely with business stakeholders, solution architects, and cross-functional teams to translate complex requirements into elegant, maintainable NetSuite customizations and integrations. This position is ideal for someone who loves problem-solving, values their craft, and approaches challenges with a positive, can-do attitude. This role is offered on a hybrid basis, with a minimum of 3 days a week being bas
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Engineering Delivery Manager (EDM) owns the delivery outcomes for one or more engineering teams ensuring that priorities, plans, and progress are clear, credible, and delivered as committed. This includes building and sustaining highperforming teams, aligning work with business priorities, and maintaining a consistent, trusted delivery narrative across the organisation. The EDM is accountable for engineering deliverables, working in close partnership with Tech
Bango enables content providers to reach more paying customers through global partnerships. Today, the Digital Vending Machine is driving the rapid growth of the subscriptions economy, powering choice and control for subscribers. The worlds largest content providers, including Amazon, Google and Microsoft trust Bango technology to reach subscribers everywhere. Bango, where people subscribe. Role - At Bango, the Engineering Delivery Manager (EDM) owns the delivery outcomes for one or more engineering teams ensuring that priorities, plans, and progress are clear, credible, and delivered as committed. This includes building and sustaining highperforming teams, aligning work with business priorities, and maintaining a consistent, trusted delivery narrative across the organisation. The EDM is accountable for engineering deliverables, working in close partnership with Tech
Company Description - Cell therapies have been shown to cure devastating and previously untreatable diseases like cancer by re-programming the patient's own immune system. Giving more patients access to these life-saving therapies requires a revolution in manufacturing and process automation. Cellular Origins, a TTP Company, is enabling scalable, cost-effective and efficient manufacture of cell and gene therapies. Our technology addresses the challenges associated with manufacturing at scale with an elegant robotic manufacturing automation solution that reduces cost and labour, eliminates human error, and increases efficiency. Job Description - You will design and implement PLC control systems using Beckhoff TwinCAT. You will be responsible for delivering PLC systems that integrate with Cellular Origins' factory software architecture to allow remote control of machine
Company Description - Cell therapies have been shown to cure devastating and previously untreatable diseases like cancer by re-programming the patient's own immune system. Giving more patients access to these life-saving therapies requires a revolution in manufacturing and process automation. Cellular Origins, a TTP Company, is enabling scalable, cost-effective and efficient manufacture of cell and gene therapies. Our technology addresses the challenges associated with manufacturing at scale with an elegant robotic manufacturing automation solution that reduces cost and labour, eliminates human error, and increases efficiency. Job Description - You will design and implement PLC control systems using Beckhoff TwinCAT. You will be responsible for delivering PLC systems that integrate with Cellular Origins' factory software architecture to allow remote control of machine
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
Large-scale data processing; data modeling; holistic, intent-based API design
676 exact matches jobs are outside your preferred location
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Senior API Technical Consultant (GraphQL Specialist)
Senior API Technical Consultant (GraphQL Specialist)
Staffworx Limited
Slough (SL1)
market rates, outside IR35, 2 days on site
Lead the designand evolution of our API schemas, ensuring they meet the complex demands of a rapidly growing platform. * Expert levelGraphQL, including advanced API design, schema evolution, performance optimisation.
Lead the designand evolution of our API schemas, ensuring they meet the complex demands of a rapidly growing platform. * Expert levelGraphQL, including advanced API design, schema evolution, performance optimisation.
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Senior Backend Engineer TypeScript Node API
Senior Backend Engineer TypeScript Node API
Client Server
The City, City of London (EC4), EC2V
£85000 - £100000 per annum + shares + benefits
Senior Backend Engineer / Developer (TypeScript Node API) London / WFH to £100k
Senior Backend Engineer / Developer (TypeScript Node API) London / WFH to £100k
NEWPREMIUM
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Mastercard Developers ( is the primary API platform for Mastercard partners to access a diverse range of payment, data, loyalty, and security APIs. The team is responsible for delivering an experience that ensures developers can quickly find the right API, assess its technical capabilities and integrate it into new and innovative solutions. Act as subject matter expert for Mastercard Developers API Platform and services to support customer integrations on occasion - Proven track record in API based products
Mastercard Developers ( is the primary API platform for Mastercard partners to access a diverse range of payment, data, loyalty, and security APIs. The team is responsible for delivering an experience that ensures developers can quickly find the right API, assess its technical capabilities and integrate it into new and innovative solutions. Act as subject matter expert for Mastercard Developers API Platform and services to support customer integrations on occasion - Proven track record in API based products
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Product management, within digital services or public sector environments experienced with Apigee (preferred) or similar API management platforms, including API publishing, monitoring, and access control. * Lead the end-to-end product lifecycle for the onboarding service, from discovery through delivery and iteration for Clients API providers. * Define the long-term vision and strategy for API products, focusing on the needs of developers, clinicians, and patients. * Proven experience in product management, ideally within digital services or public sector environments experienced with Apigee (preferred) or similar API management platforms, including API publishing, monitoring, and access control. * Lead the end-to-end product lifecycle for the onboarding service, from
Product management, within digital services or public sector environments experienced with Apigee (preferred) or similar API management platforms, including API publishing, monitoring, and access control. * Lead the end-to-end product lifecycle for the onboarding service, from discovery through delivery and iteration for Clients API providers. * Define the long-term vision and strategy for API products, focusing on the needs of developers, clinicians, and patients. * Proven experience in product management, ideally within digital services or public sector environments experienced with Apigee (preferred) or similar API management platforms, including API publishing, monitoring, and access control. * Lead the end-to-end product lifecycle for the onboarding service, from
TypeScript Developer Full Stack - Fintech
TypeScript Developer Full Stack - Fintech
Client Server
Shoreditch, East London (E1), EC2A
£50000 - £60000 per annum + benefits
TypeScript Developer / Engineer (Full Stack API React) London / WFH to £60k - Apply now to find out more about this TypeScript Developer / Engineer (Full Stack API React) opportunity.
TypeScript Developer / Engineer (Full Stack API React) London / WFH to £60k - Apply now to find out more about this TypeScript Developer / Engineer (Full Stack API React) opportunity.
PREMIUM
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This role is ideal for someone who specialises in system integration, API design, and cloud-based architecture (Azure) and enjoys shaping strategy as well as guiding delivery teams. * Design and govern API-led integrations, interface specifications, message schemas, and data flows. * Hands-on knowledge of Microsoft Azure integration services (API Management, Service Bus, Logic Apps, Event Grid, etc.) * Strong understanding of enterprise integration patterns, API management platforms (Apigee/Azure API Mgmt)
This role is ideal for someone who specialises in system integration, API design, and cloud-based architecture (Azure) and enjoys shaping strategy as well as guiding delivery teams. * Design and govern API-led integrations, interface specifications, message schemas, and data flows. * Hands-on knowledge of Microsoft Azure integration services (API Management, Service Bus, Logic Apps, Event Grid, etc.) * Strong understanding of enterprise integration patterns, API management platforms (Apigee/Azure API Mgmt)
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Solid understanding of REST API development, integrations, and modern application architecture.
Solid understanding of REST API development, integrations, and modern application architecture.
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Senior Service Management & Integration Solution Architect
Senior Service Management & Integration Solution Architect
DXC Technology
London
Unspecified Competitive Salary & Benefits
Extensive knowledge and experience with modern ITSM tools, ITIL and API technologies, solutions, and architectures. * Service Integrations using API based policies
Extensive knowledge and experience with modern ITSM tools, ITIL and API technologies, solutions, and architectures. * Service Integrations using API based policies
PREMIUM
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Champion best practices across testing disciplines including unit, integration, UI, API, and performance * Knowledge of web, mobile, API/microservices testing and contract testing (e.g. PACT)
Champion best practices across testing disciplines including unit, integration, UI, API, and performance * Knowledge of web, mobile, API/microservices testing and contract testing (e.g. PACT)
PREMIUM
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API-first and integration platforms
API-first and integration platforms
The successful candidate will demonstrate significant expertise in Microsoft Azure services, Web API, Azure App Service, .NET Core, and Visual Studio. * Design and implement scalable technology solutions using Web API, Azure App Service, and .NET Core to satisfy business requirements and enhance operational efficiency. * Define architectural patterns for microservices and API management. Azure API Development * Develop and maintain APIs using Azure API Management, Web API, and .NET Core to enable secure and efficient integrations. * Ensure API performance, security, and compliance with best practices. * Monitor and optimize application and API performance using Azure Monitor, Application Insights, and Log Analytics. * Expertise in Mic
The successful candidate will demonstrate significant expertise in Microsoft Azure services, Web API, Azure App Service, .NET Core, and Visual Studio. * Design and implement scalable technology solutions using Web API, Azure App Service, and .NET Core to satisfy business requirements and enhance operational efficiency. * Define architectural patterns for microservices and API management. Azure API Development * Develop and maintain APIs using Azure API Management, Web API, and .NET Core to enable secure and efficient integrations. * Ensure API performance, security, and compliance with best practices. * Monitor and optimize application and API performance using Azure Monitor, Application Insights, and Log Analytics. * Expertise in Mic
)
Utilise Fetch API to automate interactions with web services and validate data flows.
Utilise Fetch API to automate interactions with web services and validate data flows.
FEATURED
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Senior .Net Integration Developer
Senior .Net Integration Developer
Rise Technical
Maidenhead, Berkshire
£50000.00 - £70000.00 per annum + + Training + Holiday
You will use your expertise in C#/.NET and modern APIs (REST, WebAPI, JSON, OAuth2) to build fault-tolerant, event-driven integrations, support customers and partners with API usage, and deliver clear, high-quality documentation while maintaining security, GDPR compliance, and operational reliability. Taking integration leadership, you will design and maintain well-documented financial and third-party integrations built on modern API standards. * Support customers and partners with integration setup and API usage
You will use your expertise in C#/.NET and modern APIs (REST, WebAPI, JSON, OAuth2) to build fault-tolerant, event-driven integrations, support customers and partners with API usage, and deliver clear, high-quality documentation while maintaining security, GDPR compliance, and operational reliability. Taking integration leadership, you will design and maintain well-documented financial and third-party integrations built on modern API standards. * Support customers and partners with integration setup and API usage
)
Senior .Net Integration Developer
Senior .Net Integration Developer
Rise Technical Recruitment Limited
Maidenhead (SL6)
£50000.00 - £70000.00 per annum + + Training + Holiday
You will use your expertise in C#/.NET and modern APIs (REST, WebAPI, JSON, OAuth2) to build fault-tolerant, event-driven integrations, support customers and partners with API usage, and deliver clear, high-quality documentation while maintaining security, GDPR compliance, and operational reliability. Taking integration leadership, you will design and maintain well-documented financial and third-party integrations built on modern API standards. * Support customers and partners with integration setup and API usage
You will use your expertise in C#/.NET and modern APIs (REST, WebAPI, JSON, OAuth2) to build fault-tolerant, event-driven integrations, support customers and partners with API usage, and deliver clear, high-quality documentation while maintaining security, GDPR compliance, and operational reliability. Taking integration leadership, you will design and maintain well-documented financial and third-party integrations built on modern API standards. * Support customers and partners with integration setup and API usage
PREMIUM
Extensive experience in API development both REST and SOAP. Experience with IntelliJ, Eclipse editor api.
Extensive experience in API development both REST and SOAP. Experience with IntelliJ, Eclipse editor api.
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- The City, City (EC4)
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- Shoreditch
- Southwark
- The City, City (EC2)
- Hinxton
- Ireland
- Lambeth
- Arundel Heights
- Bloomsbury
- City of London
- Cambridge
- Central London
- West End
- South East London
- Milton Keynes
- East London
- West London
- Northampton
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- London
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